Sunday, September 25, 2022

Nicotinamide Mononucleotide (NMN)

NMN Health Benefits

At one point in time, we have all heard the words Fountain of Youth, which you might already know is a mythical pool of water where if one bathes or drinks from it, their youth gets restored.

Yes, most of us wished that it was real, but it was just a myth, an entertaining story passed down to us, and now we have to deal with aging, which even World Health Organization (WHO) in June 2018 classified aging as a disease. This event led to researchers’ search to create their fountain of youth through novel therapeutics to slow down or reverse aging.

Over the years, scientists came upon the molecule Nicotinamide mononucleotide and researched it. Now, this NMN is publicized as the fountain of youth claimed to have an anti-aging effect.

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Nicotinamide Mononucleotide (NMN)

NMN stands for Nicotinamide mononucleotide, which is a molecule that occurs naturally in all living forms. It is a family of nucleotides, an organic molecule that is found in sugar and carbohydrates, and vitamin B3, and this molecule is the elementary unit of RNA and DNA.

What NMN does is that the Nicotinamide Adenine Dinucleotide or NAD+ is present in our cells which does a lot of crucial work like helping our cells keep functioning properly and repair the DNAs that are damaged.

The production of these cells NAD starts decreasing when we age and when this happens, health issues arise, and so does aging. So to stop this from happening, this is where NMN comes into play; when the levels of NMN are high, the production of NAD also increases.

The work of NMN doesn’t stop there as it has an overall impact on our bodies. Some of those health benefits are listed below.

Nicotinamide Mononucleotide (NMN)

NMN Health Benefits

Anti-Aging

When you start aging, your body’s NAD level also starts declining, and then your body starts showing various signs of health problems. Studies have shown that when you increase the level of NAD, the body’s process of aging also slows down. The NAD level can be boosted by giving the user an adequate amount of NMN.

Sirtuin

Another reason for anti-aging is sirtuin, and they are known to repair damages, maintain cellular health, and participate in aging-related problems. Sirtuins or guardian of genes needs NAD+ for its activation that’s why keeping the NMN levels in our body is essential.

Lessen Chances of Obesity

NMN supplements help decrease the chances of obesity and problems connected to obesity and also helps in weight loss as NMN provides essential enzymes. It also aids in having a proper body weight.

Users who used NMN supplements reported an increase in lean mass and decrease in fat mass. It also improves your muscle strength and endurance, making you fit with no evident side effects.

Vascular Health and Blood Flow

Our skeletal muscles need important energy molecules like fatty acids and glucose to stay in a healthy state. It must receive an adequate amount of NMN as most of our stability and movement come from our skeletal muscles.

NMN also helps reactivate blood flow. Research done by Dr. David Sinclair discovered that with the decline of age, the endothelial cells that line the blood vessels stop working properly, which also results in a lack of proper supply of oxygen nutrients, eliminating waste and exchange of heat. But studies have shown that taking NMN supplements aid in forming new blood vessels by improving the endothelial cells.

Memory Improvement

Studies showed that the use of both Nicotinamide riboside and NMN improved motor control, learning, and memory and showed fewer signs of inflammation. The concentration level of NMN users also showed positive signs.

Boost Energy Levels

NMN has shown an increase in energy levels among people with the use of NMN. The doses taken were 250 mg or 500 mg depending on the person, after which they started feeling a boost in energy.

Studies conducted on older mice also show an increase of 80 percent in endurance and stamina when taken NMN orally.

Foods with NMN

Foods that contain Nicotinamide mononucleotide naturally:

  • Broccoli
  • Avocado
  • Raw beef
  • Tomato
  • Cabbage
  • Edamame (immature soybeans)
  • Cucumber

Note that even though these foods contain NMN, it doesn’t have the sufficient amount to be effective, so it cannot increase the NAD levels. The amount we get from our daily food intake doesn’t provide the necessary amount of NMN. That’s why people usually opt for NMN supplements which makes them more helpful in boosting the levels.

Effectiveness of NMN

The level of NMN in your body automatically starts increasing within moments of consuming it, and after some hours, the level of NAD+ also increases. But for this molecule to start working and showing effects, it takes around 2 to 3 weeks, as reported by users. Sometimes it also takes some months to show the total result. So NMN supplements do the work, it says!

Safety Check of NMN

After all the animal testing, a clinical study was also conducted on humans in Japan to check whether NMN supplements are safe for human use. They were given NMN dosages of 100, 250, and 500 mg, which didn’t show any signs or symptoms of side effects. The results were shown in November 2019 in the Endocrine Journal. This clinical study proved that NMN is safe to use, and FDA also gave its approval as a dietary supplement.

Conclusion

Nicotinamide mononucleotide (NMN) supplements come in various forms like capsules, tablets, and powder form. So even if the fountain of youth doesn’t exist, at least you get NMN supplements, the next best thing available for anti-aging. (1)

Till now, NMN supplements have been showing promising results. So in the coming years, with the advancement of science and medicine, the anti-aging field will be even more developed than it is at present.

And we might get a pill similar to the fountain of youth or close to help people regain their youthful energy and look and live a healthy life.

 

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Jason Moore
Jason Moorehttps://nchosp.org
I've been a bodybuilder and fitness enthusiast for over 15 years. I'm also a Karate black belt and personal trainer with a PHD in sports nutrition.

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